• The Lai laboratory

    Physical Chemistry of RNA in Protocell

    Our lab investigates the complex world of biological systems, focusing mainly on the structural dynamics and functional connections of RNA molecules. We carefully examine RNA behavior in various chemical environments using spectroscopy methods such as fluorescence and electron spin resonance (ESR). Our research combines experimental research with theoretical insights, allowing us to reveal the dynamic nature of RNA. We aim to enhance the scientific community's understanding of RNA's critical roles in essential biological processes.

  • Research Projects

    Questions we ask.

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    How life emerged?

    We study how current biology could evolve from the RNA world. We build and create protocells to understand why cellular structure is essential to the current biology.

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    How RNA works?

    The structural dynamic of functional RNA correlates with its activity. Such correlation is often complex and largely depends on environments. We use spin-label ESR spectroscopy to resolve the complex structural dynamics of functional RNAs.

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    How to pick useful RNAs?

    We use in-vitro selection as a strategy to select functional RNAs for bioengineering and fundamental research purposes.

  • Contact Us

    歡迎對生物物理化學有興趣的同學加入實驗室!We welcome researchers interested in physical chemistry, biological chemistry, and molecular biology.

    E-mail: yeichenlai@nchu.edu.tw

    Tel: 04-2284-0411 ext.614 (office); ext. 504 (Lab)

    Address:

    Room 614, Department of Chemistry, National Chung Hsing University

    145 Xingda Rd., South Dist., Taichung City, 402, Taiwan

    (402 台中市南區興大路145號 國立中興大學化學系 614室)